sarah hudson ul. Following a sabbatical from academia spent working as a raft guide and safety kayaker on 3 continents, I completed my PhD in 2006 on the immobilization of enzymes onto novel mesoporous supports and their catalytic properties in the University of Limerick. L. monocytogenes infections can cause life-long effects in the elderly a sarah.hudson@ul.ie Keywords: Mesoporous matrices; Nisin A; Controlled release; Antimicrobial; periodic mesoporous organosilanes; simulated gastrointestinal fluid; bacteriocins Abstract Mesoporous matrices of different pore size and chemical composition were explored as potential delivery matrices for the broad spectrum bacteriocin, nisin A. We examine the factors that influence the optimisation of mammalian and microbial fermentation processes for the production of small and large molecules. They explore the solution and solid-state behaviour of these molecules both during formulation/manufacture into medicines and in biorelevant environments. Work location(s) 2 position(s) available at. *Corresponding author: Sarah.Hudson@ul.ie 10 Abstract Nanoparticles of poorly water-soluble drugs were prepared in suspension via antisolvent precipitation in order to improve their dissolution behaviour. Electronic address: Sarah.Hudson@ul.ie. 4 Synthesis and Solid State Pharmaceutical Centre, Department of Chemical Sciences, The Bernal Institute, University of Limerick, Limerick, V94 T9PX, Ireland. The Journal of Physical Chemistry B 109 (41), 19496-19506 Jakki Cooney Dr. Department of Life Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Co. I will be forever grateful for all her help, anything I achieve will be thanks to the mentoring I received from you during the last four years. Research and Teaching Interests. Nucleation and particle growth, release kinetics, bioavailability. She is a funded investigator in the Synthesis and Solid State Pharmaceutical Research Centre (SSPC) since 2013. She was awarded a masters in Chemistry from Trinity a year later, where she worked on the photophysical properties of rhenium complexes with Prof John Kelly. We study the effects of the components bio-relevant media on the solution and crystallisation behaviour of active pharmaceutical ingredients in vitro quantifying drug-component interactions and their influence on nucleation and crystallisation events. I studied Chemistry in Trinity College Dublin which led to a research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties. Pictured with MITs Professor Robert Langer on his recent visit to UL to deliver the second in the Bernal Distinguished Lecture Series, is Dr Sarah Hudson. Specialist Diploma in Teaching, Learning and Scholarship, Ph.D. Chemistry University of Limerick. by research in Chemistry, Trinity College Dublin. My research focuses on the control of nucleation of organic pharmaceutical molecules and the development of crystallisation technologies to improve the bioavailability of such molecules. Jakki Cooney Dr. Department of Life Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Search for more papers by this author. Department of Chemical and Environmental Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Co. This saves a cookie "__cfduid" to apply security settings on a per-client basis. Office: MS2-019, Control your personal Cookie Services here.